Monoclonal Anti-COG2 antibody produced in mouse
SIGMA/WH0022796M9 - clone 4C8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-LDLC; Anti-component of oligomeric golgi complex 2
Product Type: Chemical
Enhanced Validation-RNAi Western blot analysis of COG2 over-expressed 293 cell line, cotransfected with COG2 Validated Chimera RNAi. Blot probed with COG2 monoclonal antibody, clone 4C8. GAPDH (36.1 kDa) used as specificity and loading control.
Western Blotting Western Blot analysis of COG2 expression in transfected 293T cell line by COG2 monoclonal antibody, clone 4C8. Lanes Lane 1: COG2 transfected lysate (83.2 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (36.63 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4C8, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_007357   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q14746 |
| General description: | This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants |
| Immunogen: | COG2 (NP_031383, 639 a.a. ~ 738 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence LSESTHKYYETVSDVLNSVKKMEES |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |