Monoclonal Anti-RNF19 antibody produced in mouse
SIGMA/WH0025897M1 - clone 4E4, ascites fluid
Synonym: Anti-DKFZp566B1346; Anti-DORFIN; Anti-ring finger protein 19
Product Type: Chemical
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 4E4, monoclonal |
conjugate | unconjugated |
GenBank® accession no. | NM_015435 ![]() ![]() |
isotype | IgMκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1:500-1:1000 | |
UniProt accession no. | Q9NV58 ![]() ![]() |
General description: | The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson′s disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq) |
Immunogen: | RNF19 (NP_056250, 739 a.a. ~ 837 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MKTSCSHGSSDYHTRFATVNILPEV |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |