Monoclonal Anti-RNF19 antibody produced in mouse
SIGMA/WH0025897M1 - clone 4E4, ascites fluid
Synonym: Anti-DKFZp566B1346; Anti-DORFIN; Anti-ring finger protein 19
Product Type: Chemical
Immunoblotting Monoclonal Anti-RNF19, Cat. No. WH0025897M1 used at the antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (36.63 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4E4, monoclonal |
| conjugate | unconjugated |
| GenBank accession no. | NM_015435   |
| isotype | IgMκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q9NV58 |
| General description: | The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson′s disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq) |
| Immunogen: | RNF19 (NP_056250, 739 a.a. ~ 837 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MKTSCSHGSSDYHTRFATVNILPEV |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |