Monoclonal Anti-SNX15 antibody produced in mouse
SIGMA/WH0029907M1 - clone 1D4, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HSAF001435; Anti-sorting nexin 15
MDL Number: MFCD03455983
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 1D4, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_013306 ![]() ![]() |
isotype | IgG3κ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q9NRS6 ![]() ![]() |
General description: | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. (provided by RefSeq) |
Immunogen: | SNX15 (NP_037438, 51 a.a. ~ 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence RYSDFRKLHGDLAYTHRNLFRRLEE |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |