Monoclonal Anti-UBQLN1 antibody produced in mouse
SIGMA/WH0029979M1 - clone 1C6-A3, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DA41; Anti-DSK2; Anti-FLJ90054; Anti-PLIC1; Anti-XDRP1; Anti-ubiquilin 1
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 1C6-A3, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank accession no. | BC039294 |
isotype | IgG1κ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | immunofluorescence: suitable |
indirect ELISA: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q9UMX0 |
General description: | This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer′s and Parkinson′s disease. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
Immunogen: | UBQLN1 (AAH39294, 1 a.a. ~ 589 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MAESGESGGPPGSQDSAAGAEGAGT |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |