Monoclonal Anti-DMAP1 antibody produced in mouse
SIGMA/WH0055929M1 - clone 2G12, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DKFZp686L09142; Anti-DNA methyltransferase 1 associated protein 1; Anti-DNMAP1; Anti-DNMTAP1; Anti-EAF2; Anti-FLJ11543; Anti-KIAA1425; Anti-SWC4
MDL Number: MFCD07370300
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to DMAP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 μg/mL]
Western Blotting Western Blot analysis of DMAP1 expression in transfected 293T cell line by DMAP1 monoclonal antibody, clone 2G12. Lanes Lane 1: DMAP1 transfected lysate (53 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2G12, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | NM_019100   |
| isotype | IgG1κ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9NPF5 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. (provided by RefSeq) |
| Immunogen: | DMAP1 (NP_061973, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MATGADVRDILELGGPEGDAASGTI |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |