Monoclonal Anti-PPIL4 antibody produced in mouse
SIGMA/WH0085313M1 - clone 1C10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HDCME13P; Anti-peptidylprolyl isomerase (cyclophilin)-like 4
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to PPIL4 on HeLa cell. [antibody concentration 10 μg/mL]
Enhanced Validation-RNAi Western blot analysis of PPIL4 over-expressed 293 cell line, cotransfected with PPIL4 Validated Chimera RNAi. Blot probed with PPIL4 monoclonal antibody, clone 1C10. GAPDH (36.1 kDa) used as specificity and loading control.
Western Blotting PPIL4 monoclonal antibody, clone 1C10 Western Blot analysis of PPIL4 expression in HeLa S3 NE.
Western Blotting Western Blot analysis of PPIL4 expression in transfected 293T cell line by PPIL4 monoclonal antibody, clone 1C10. Lanes Lane 1: PPIL4 transfected lysate (57.2 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (33.66 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1C10, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_139126   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q8WUA2 |
| Biochem/physiol Actions: | Peptidylprolyl isomerase like 4 (PPIL4) may have a role in the immune system. Polymorphisms in the PPIL4 gene may enhance inflammation during rheumatoid arthritis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Peptidylprolyl isomerase like 4 (PPIL4) is part of the cyclophilin family. This family has a role in protein folding, human immunodeficiency virus-1 (HIV-1) infection and immunosuppression by cyclosporin A. The gene encoding PPIL4 is localized on human chromosome 6q24-->q25. It possesses a PPIase motif, a lysine-rich domain, a RNA recognition motif and two bipartite nuclear targeting sequences. PPIL4 is expressed in the kidneys and other tissues. |
| Immunogen: | PPIL4 (NP_624311, 395 a.a. ~ 466 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence EKEDEDYMPIKNTNQDIYREMGFGH |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |