Monoclonal Anti-IL31RA antibody produced in mouse
SIGMA/WH0133396M1 - clone 3A10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CRL; Anti-CRL3; Anti-GLMR; Anti-GPL; Anti-IL31RA; Anti-MGC125346; Anti-PRO21384; Anti-interleukin 31 receptor A
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to IL31RA on formalin-fixed paraffin-embedded human spleen. [antibody concentration 3 μg/mL]
Enhanced Validation-RNAi Western blot analysis of IL31RA over-expressed 293 cell line, cotransfected with IL31RA Validated Chimera RNAi. Blot probed with IL31RA monoclonal antibody, clone 3A10. GAPDH (36.1 kDa) used as specificity and loading control.
Western Blotting Western Blot analysis of IL31RA expression in transfected 293T cell line by IL31RA monoclonal antibody, clone 3A10. Lanes Lane 1: IL31RA transfected lysate (83 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3A10, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_139017   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q8NI17 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM |
| Immunogen: | IL31RA (NP_620586, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence LPAKPENISCVYYYRKNLTCTWSPG |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |