Monoclonal Anti-ADAMTS17 antibody produced in mouse
SIGMA/WH0170691M1 - clone 3B7, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-ADAM metallopeptidase with thrombospondin type 1 motif, 17; Anti-FLJ32769
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to ADAMTS17 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 1.2 μg/mL]
Western Blotting ADAMTS17 monoclonal antibody, clone 3B7. Western Blot analysis of ADAMTS17 expression in NIH/3T3.
Western Blotting ADAMTS17 monoclonal antibody, clone 3B7 Western Blot analysis of ADAMTS17 expression in A-431.
Western Blotting QC Western Blot detection against Immunogen (37.62 kDa).
ELISA Detection limit for recombinant GST tagged ADAMTS17 is 0.3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3B7, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_139057   |
| isotype | IgG1κ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q8TE56 |
| Biochem/physiol Actions: | ADAM metallopeptidase with thrombospondin type 1 motif 17 (ADAMTS17) is associated with Weill-Marchesani-like syndrome. Knockdown of the protein has been shown to prevent the growth of breast cancer cells in vitro. ADAMTS17 binds to the extracellular matrix. |
| General description: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined. (provided by RefSeq) |
| Immunogen: | ADAMTS17 (NP_620688, 543 a.a. ~ 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DGDWSPWGAWSMCSRTCGTGARFRQ |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |