Monoclonal Anti-MAFA antibody produced in mouse
SIGMA/WH0389692M1 - clone 2F1, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-RIPE3b1; Anti-hMafA; Anti-v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
MDL Number: MFCD03455547
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 2F1, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_201589 ![]() ![]() |
isotype | IgG2aκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q8NHW3 ![]() ![]() |
Biochem/physiol Actions: | MAF bZIP transcription factor A (MAFA) modulates genes which are involved in pancreatic β-cell function and the protein itself is critical for the functioning of β-cells. It functions as a regulator to enhance the expression of genes which have a role in glucose-induced insulin secretion. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM |
Immunogen: | MAFA (NP_963883, 222 a.a. ~ 308 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence LEERFSDDQLVSMSVRELNRQLRGF |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
WGK Germany | nwg |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |