Triton™ X-100 reduced
SIGMA/X100RS
Synonym: Polyoxyethylene (10) isooctylcyclohexyl ether
CAS Number: 92046-34-9
MDL Number: MFCD00167048
Linear Formula: 4-(C8H17)C6H10(OCH2CH2)nOH, n~10
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X100RS-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X100RS-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X100RS-5G
| absorption | ≤0.25 at 277 nm in H2O at 0.5% |
| aggregation number | 100-155 |
| biological source | synthetic (oragnic) |
| CMC | 0.2-0.9 |
| density | 1.029 g/mL at 25 °C (lit.) |
| description | non-ionic |
| form | viscous liquid |
| HLB | 13.5 |
| InChI | 1S/C28H56O8/c1-27(2,3)24- |
| InChI key | QQJNBKDKLMCALZ-UHFFFAOYSA |
| mol wt | average mol wt 625 |
| micellar average mol wt 80,000 | |
| mp | 48 -50 °C (118 - 122 °F) |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | CC(C)(C)CC(C)(C)C1CCC(CC1 |
| solubility | water: soluble, clear to slightly hazy, colorless |
| transition temp | cloud point 65 °C |
| Application: | Triton™ X-100 reduced has been used: • in nuclear magnetic resonance (NMR) sample tube for lysing/rupturing the 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) phospholipid vesicles • in cell permeabilization • as a component in Tris/HCl to determine hydrolysis of the esters for enzyme activity assays |
| Features and Benefits: | • Non-ionic surfactant • Improves solubility and dispersibility of substances • Excellent wetting properties • Enhances emulsification • High purity product for research applications |
| General description: | Triton™ X-100 reduced is a versatile nonionic surfactant featuring a hydrophilic polyethylene oxide chain, commonly employed as a laboratory detergent. Its applications span various purposes, including cell lysis to extract proteins or organelles, permeabilizing the membranes of living cells, and serving as a vital component in lysis buffers. Widely utilized in biochemical and cell biology research, Triton™ X-100 facilitates the isolation of lipid rafts, enhancing the solubility and dispersibility of substances. With a reduced polyoxyethylene content of approximately 10, this product exhibits excellent wetting properties and emulsification enhancement. In cell biology, Triton™ X-100 plays a crucial role in solubilizing membrane-bound proteins, preserving their native conformation in solution. Furthermore, Triton™ X-100 reduced, resulting from the full hydrogenation of the benzene moiety of TX-100 to a cyclohexane derivative, has been associated with potential benefits in enzyme digestion enhancement and effects on the photoisomerization of bacteriorhodopsin. The versatility of Triton™ X-100 in various research applications underscores its significance as a fundamental tool in biochemical and cell biology investigations. |
| Legal Information: | Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 5, 25 g in glass bottle |
| Preparation Note: | Hydrogenated to reduce UV absorbance. |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 - H411 |
| Precautionary statements | P273 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| mp | 48 -50 °C (118 - 122 °F) |
| Density | 1.029 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12161900 |