Xanthine sodium salt
SIGMA/X2502 - ≥99%
Synonym: 2,6-Dihydroxypurine
CAS Number: 1196-43-6
Empirical Formula (Hill Notation): C5H3N4NaO2
Molecular Weight: 174.09
MDL Number: MFCD00069699
Linear Formula: C5H3N4NaO2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X2502-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X2502-5G
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| assay | ≥99% |
| biological source | synthetic (organic) |
| form | powder |
| impurities | ≤4% total solvent |
| InChI | 1S/C5H4N4O2.Na.H/c10-4-2- |
| InChI key | JAZQMXVZANZJSO-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | [Na].O=C1NC(=O)c2[nH]cnc2 |
| solubility | dilute NaOH: soluble, clear to slightly hazy |
| Application: | Xanthine sodium salt has been used as a component of substrate solution for xanthine oxidase during superoxide dismutase (SOD) assay. It has also been used as a supplement in a special-conditioned medium to culture Swiss 3T3 fibroblasts stably transfected with tetracycline (tet)-controlled transactivator and transactivator-controlled tissue transglutaminase cDNA [39] constructs (clone TG3). |
| Biochem/physiol Actions: | Xanthine acts as a substrate for xanthine oxidase. It elevates cellular cyclic AMP levels by preventing its breakdown and metabolism by inhibition of tissue phosphodiesterases. Xanthine also exhibits anti-inflammatory properties either by the release of anti-inflammatory cytokines or gene transcription regulation or histone deacetylase activation. All these properties of xanthine aid in the relaxation of smooth muscles of the bronchial tree. |
| General description: | Xanthine is an intermediate of purine nucleotide metabolism. It is found in most body tissues and fluids. Xanthine derivatives are present in coffee, tea, and chocolate. |
| Packaging: | 5, 10, 25 g in poly bottle |
| Symbol |  GHS08 |
| Signal word | Warning |
| Hazard statements | H371 |
| Precautionary statements | P260 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-68/20/21/22 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| UNSPSC | 41106305 |