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Xestospongin C

SIGMA/X2628 - film

Synonym: XeC

CAS Number: 88903-69-9
Empirical Formula (Hill Notation): C28H50N2O2
Molecular Weight: 446.71
MDL Number: MFCD01862629
Linear Formula: C28 H50 N2 O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-X2628-10UG 10 µg
 $476.00
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45-X2628-50UG 50 µg
 $1720.00
1/EA		 Add To Favorites

 

color colorless
form film
InChI 1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1
InChI key PQYOPBRFUUEHRC-HCKQMYSWSA-N
Quality Level 100 
shipped in dry ice
SMILES string [H][C@@]12CCCCCC[C@@]3([H])CCCN4CC[C@@]([H])(CCCCCC[C@]5([H])CCCN(CC1)[C@@]5([H])O2)O[C@@]34[H]
solubility DMSO: soluble
storage temp. −20°C
Biochem/physiol Actions: Xestospongin C is a potent, reversible and membrane-permeable blocker of IP3-mediated Ca2+ release (IC50=358 nM).
Biochem/physiol Actions: Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. Reversibly blocks bradykinin- and carbamylcholine- Ca2+ efflux from the endoplasmic reticulum stores.
Features and Benefits: This compound is featured on the InsP3/Ryanodine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Synthetic form of the macrocyclic bis-1-oxaquinolizidine isolated from the Okanowan marine sponge.
Packaging: 10, 50 μg in glass bottle
Packaging: Package under nitrogen, tightly sealed.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352200

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