XAV939
SIGMA/X3004 - ≥98% (HPLC)
Synonym: 3,5,7,8-
CAS Number: 284028-89-3
Empirical Formula (Hill Notation): C14H11F3N2OS
Molecular Weight: 312.31
MDL Number: MFCD16879017
Linear Formula: C14H11F3N2OS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C14H11F3N2OS/c15-14(16 |
InChI key | KLGQSVMIPOVQAX-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | FC(F)(F)c1ccc(cc1)C2=NC3= |
solubility | DMSO: 5 mg/mL, clear |
storage temp. | room temp |
Application: | XAV939 has been used in the inhibition • of tankyrase in neuroblastoma cell lines • of diphtheria toxin-like ADP-ribosyltransferases (ARTD) in medulloblastoma cells • of wnt signalling in human induced pluripotent stem cells (hiPSCs) |
Biochem/physiol Actions: | XAV939 is a cell-permeable dihydrothiopyranopyrimidi |
Biochem/physiol Actions: | XAV939 is a Tankyrase inhibitor (thereby inhibiting Wnt / β-catenin signaling) |
Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here ![]() ![]() |
Other Notes: | XAV939 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the XAV939 probe summary ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
Hazard Codes | T |
Risk Statements | 25-36 |
Safety Statements | 26-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |