Xanthine
SIGMA/X7375 - ≥99%
Synonym: 2,6-Dihydroxypurine
CAS Number: 69-89-6
Empirical Formula (Hill Notation): C5H4N4O2
Molecular Weight: 152.11
EC Number: 200-718-6
MDL Number: MFCD00078453
Linear Formula: C5H4N4O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X7375-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X7375-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: X7375-25G
| assay | ≥99% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C5H4N4O2/c10-4-2-3(7-1 |
| InChI key | LRFVTYWOQMYALW-UHFFFAOYSA |
| Quality Level | 300  |
| SMILES string | O=C1NC(=O)c2nc[nH]c2N1 |
| solubility | 1 M NaOH: soluble 50 mg/mL, clear to slightly hazy |
| NaOH: freely soluble | |
| NH4OH: freely soluble |
| Application: | Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay. It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells and algal cells. |
| Biochem/physiol Actions: | A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine. |
| General description: | Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds. |
| Packaging: | 10, 25, 100 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36-43 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥99% |
| UNSPSC | 41106305 |