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YFLLRNP trifluoroacetate

SIGMA/Y1396 - ≥98%

Synonym: L-Tyrosyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparaginyl-L-Proline; Tyr-Phe-Leu-Leu-Arg-Asn-Pro; YFLLRNP-OH

Empirical Formula (Hill Notation): C45H67N11O10 · xC2HF3O2
Molecular Weight: 922.08 (free base basis)
MDL Number: MFCD16879019
Linear Formula: C45H67N11O10 · xC2HF3O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y1396-1MG 1 mg
 $193.00
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assay ≥98%
form solid
InChI 1S/C45H67N11O10.C2HF3O2/c1-25(2)20-32(40(61)51-31(12-8-18-50-45(48)49)39(60)55-35(24-37(47)58)43(64)56-19-9-13-36(56)44(65)66)53-41(62)33(21-26(3)4)54-42(63)34(23-27-10-6-5-7-11-27)52-38(59)30(46)22-28-14-16-29(57)17-15-28;3-2(4,5)1(6)7/h5-7,10-11,14-17,25-26,30-36,57H,8-9,12-13,18-24,46H2,1-4H3,(H2,47,58)(H,51,61)(H,52,59)(H,53,62)(H,54,63)(H,55,60)(H,65,66)(H4,48,49,50);(H,6,7)/t30-,31-,32-,33-,34-,35-,36-;/m0./s1
InChI key HMDRRCMAXMJXKF-WDYYMHPRSA-N
Quality Level 100 
SMILES string OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N3CCC[C@H]3C(O)=O
solubility deionized water: 1 mg/mL
storage temp. −20°C
Application: YFLLRNP trifluoroacetate may be used as a powerful tool for differentiating the numerous possible activation states of the platelet thrombin receptor.
Biochem/physiol Actions: YFLLRNP is a Galpha12/13-stimulating peptide that activates the alpha granule secretion due to costimulation with either ADP or serotonin/epinephrine.
Biochem/physiol Actions: YFLLRNP is a PAR-1-specific partial agonist.
Biochem/physiol Actions: YFLLRNP is a PAR-1-specific partial agonist. The compound selectively activates the G(12/13) signaling cascade resulting in platelet shape.
Packaging: 1 mg in glass bottle
Preparation Note: YFLLRNP trifluoroacetate dissolves in deionized water at 1 mg/mL.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
Storage Temp. −20°C
UNSPSC 51111800

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