α-Zearalenol
SIGMA/Z0166
Synonym: 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone
CAS Number: 36455-72-8
Empirical Formula (Hill Notation): C18H24O5
Molecular Weight: 320.38
MDL Number: MFCD16657008
Linear Formula: C18H24O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C18H24O5/c1-12-6-5-9-1 |
| InChI key | FPQFYIAXQDXNOR-QDKLYSGJSA |
| Quality Level | 200  |
| SMILES string | C[C@H]1CCC[C@H](O)CCCC=C |
| solubility | methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | α-Zearalenol has been used: • as an analytical standard in the quantification of mycotoxins from animal feed • to evaluate its oestrogenic activity on boar sperm motility , as an anti-oestrogen control in MCF7 cells • as a reference standard in a liquid chromatography-negative ion electrospray tandem mass spectrometry with atmospheric pressure chemical ionization (LCAPCI/MS/MS) for bovine follicular fluids (FFs) quantification |
| Biochem/physiol Actions: | α-Zearalenol (α-ZOL) is a catabolite of zearalenone, synthesized majorly in granulosa cells, intestine and liver in pigs. It has estrogenic functionality. α-ZOL inhibits sperm motility in horse possibly by eliciting genotoxic effect. α-ZOL displays higher affinity towards estrogenic receptors. |
| Packaging: | 5, 10 mg in glass bottle |
| Symbol |   GHS05,GHS08 |
| Signal word | Danger |
| Hazard statements | H314 - H351 - H361fd - H371 - H412 |
| Precautionary statements | P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 45-46-63-20/21/22-48/20-52/53-62-68/20/21/22 |
| Safety Statements | 53-36/37-45-61 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |