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Zearalanone

SIGMA/Z0167

Synonym: 2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone

CAS Number: 5975-78-0
Empirical Formula (Hill Notation): C18H24O5
Molecular Weight: 320.38
MDL Number: MFCD00135821
Linear Formula: C18H24O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-Z0167-1MG 1 mg
$62.40
1/EA
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45-Z0167-5MG 5 mg
$216.00
1/EA
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assay ≥98% (TLC)
form powder
InChI 1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1
InChI key APJDQUGPCJRQRJ-LBPRGKRZSA-N
Quality Level 200 
shipped in ambient
SMILES string C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1
solubility methanol: 9.80-10.20 mg/mL, clear, colorless
sterility non-sterile
storage temp. −20°C
Application: Zearalanone has been used:
• as mycotoxin to study its effects on the histology of ovaries in pre-pubertal bitches
• as a mycotoxin to investigate its influence on selected immunological, haematological and biochemical indexes in bitches
• as a standard to develop calibration curves in order to study its effects on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
• as a standard to develop calibration curves to study its level of intoxication in women with neoplastic lesions in the reproductive tract
Biochem/physiol Actions: Zearalanone is believed to cause vulvovaginitis and estrogenic responses in swine.
General description: Zearalanone (ZEA) or F-2 toxin, a nonsteroidal estrogenic mycotoxin is produced by various Fusarium species. Fusarium graminearum is considered as the primary producer of zearalanone. It is usually seen in moldy hay, high-moisture corn, corn infected before harvest etc.
Packaging: 1, 5 mg in glass bottle
Purity ≥98% (TLC)
Storage Temp. −20°C
UNSPSC 12352200

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