Zotepine
SIGMA/Z0877
Synonym: 2-
CAS Number: 26615-21-4
Empirical Formula (Hill Notation): C18H18ClNOS
Molecular Weight: 331.86
MDL Number: MFCD00868143
Linear Formula: C18H18ClNOS
Product Type: Chemical
| assay | >98% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C18H18ClNOS/c1-20(2)9- |
| InChI key | HDOZVRUNCMBHFH-UHFFFAOYSA |
| originator | Astellas |
| Quality Level | 100  |
| SMILES string | CN(C)CCOC1=Cc2ccccc2Sc3cc |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | room temp |
| Application: | Zotepine has been used as an anti-psychotic agent: • in biophysical studies with serotonin 2A receptor (5-HT2AR) • to study its effects on the inhibition of human organic cation transporter 1 (hOCT1) • to study its protective effects on the human embryonic kidney (HEK cells) |
| Biochem/physiol Actions: | Zotepine acts as an antagonist of dopamine D1, D2, and serotonin (5-HT2A/2C) receptors, and noradrenaline transporter |
| Biochem/physiol Actions: | Zotepine is an atypical antipsychotic. |
| Features and Benefits: | This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Astellas . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H400 |
| Precautionary statements | P273 |
| Hazard Codes | T |
| Risk Statements | 25-50/53 |
| Safety Statements | 45-60-61 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |