Zimelidine dihydrochloride
SIGMA/Z101 - solid
Synonym: (Z)
CAS Number: 61129-30-4
Empirical Formula (Hill Notation): C16H17BrN2 · 2HCl
Molecular Weight: 390.15
MDL Number: MFCD00069358
Linear Formula: C16H17BrN2 · 2HCl
Product Type: Chemical
| color | white |
| form | solid |
| InChI | 1S/C16H17BrN2.2ClH/c1-19( |
| InChI key | CXGURXWCQYHDIR-ULPVBNQHSA |
| originator | AstraZeneca |
| Quality Level | 100  |
| SMILES string | Cl[H].Cl[H].[H]C(CN(C)C) |
| solubility | 0.1 M HCl: 45 mg/mL |
| H2O: 66 mg/mL |
| Application: | Zimelidine dihydrochloride has been used as a serotonin transport inhibitor to study its inhibitory role in the uptake of exogenous serotonin by bipolar cells. |
| Biochem/physiol Actions: | Zimelidine, an antidepressant, is a specific 5-hydroxytryptamine (5-HT) reuptake inhibitor, that can be used in treating phobic anxiety. It is very effective and can be tolerated well in elderly individuals. This serotonin transport inhibitor is less likely than other antidepressants to have cardiovascular side effects. Unlike other tricyclic antidepressants, Zimelidine might promote weight loss but not weight gain. |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Legal Information: | Sold with the permission of Astra AB. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352200 |