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Zimelidine dihydrochloride

SIGMA/Z101 - solid

Synonym: (Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine dihydrochloride

CAS Number: 61129-30-4
Empirical Formula (Hill Notation): C16H17BrN2 · 2HCl
Molecular Weight: 390.15
MDL Number: MFCD00069358
Linear Formula: C16H17BrN2 · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Z101-25MG 25 mg
 $161.00
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color white
form solid
InChI 1S/C16H17BrN2.2ClH/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13;;/h3-10,12H,11H2,1-2H3;2*1H/b16-9-;;
InChI key CXGURXWCQYHDIR-ULPVBNQHSA-N
originator AstraZeneca
Quality Level 100 
SMILES string Cl[H].Cl[H].[H]C(CN(C)C)=C(/c1ccc(Br)cc1)c2cccnc2
solubility 0.1 M HCl: 45 mg/mL
  H2O: 66 mg/mL
Application: Zimelidine dihydrochloride has been used as a serotonin transport inhibitor to study its inhibitory role in the uptake of exogenous serotonin by bipolar cells.
Biochem/physiol Actions: Zimelidine, an antidepressant, is a specific 5-hydroxytryptamine (5-HT) reuptake inhibitor, that can be used in treating phobic anxiety. It is very effective and can be tolerated well in elderly individuals. This serotonin transport inhibitor is less likely than other antidepressants to have cardiovascular side effects. Unlike other tricyclic antidepressants, Zimelidine might promote weight loss but not weight gain.
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Sold with the permission of Astra AB.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352200

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