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Zopolrestat

SIGMA/Z4527 - ≥98% (HPLC)

Synonym: 3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid; Alond; CP-73850; Xedia

CAS Number: 110703-94-1
Empirical Formula (Hill Notation): C19H12F3N3O3S
Molecular Weight: 419.38
MDL Number: MFCD00865476
Linear Formula: C19H12F3N3O3S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-Z4527-10MG 10 mg
$122.00
1/EA
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45-Z4527-50MG 50 mg
$475.00
1/EA
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assay ≥98% (HPLC)
color off-white to light brown
form powder
InChI 1S/C19H12F3N3O3S/c20-19(21,22)10-5-6-15-14(7-10)23-16(29-15)9-25-18(28)12-4-2-1-3-11(12)13(24-25)8-17(26)27/h1-7H,8-9H2,(H,26,27)
InChI key BCSVCWVQNOXFGL-UHFFFAOYSA-N
manufacturer/tradename Pfizer®
originator Pfizer
Quality Level 100 
SMILES string OC(=O)CC1=NN(Cc2nc3cc(ccc3s2)C(F)(F)F)C(=O)c4ccccc14
solubility DMSO: ≥20 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
Features and Benefits: This compound is featured on the Dopamine and Norepinephrine Metabolism  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Pfizer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Pfizer is a registered trademark of Pfizer, Inc.
Packaging: 10, 50 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301 - H413
Precautionary statements P273 - P301 + P310 + P330
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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