ZK 200775 hydrate
SIGMA/Z4777 - ≥98% (HPLC), powder
Synonym: Fanapanel; MPQX; [[3,4-
Empirical Formula (Hill Notation): C14H15F3N3O6P · xH2O
Molecular Weight: 409.25 (anhydrous basis)
MDL Number: MFCD18452859
Linear Formula: C14H15F3N3O6P · xH2O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | off-white to light brown |
form | powder |
InChI | 1S/C14H15F3N3O6P.H2O/c15- |
InChI key | RYQLMFHPDNKPKY-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | O.OP(O)(=O)CN1C(=O)C(=O)N |
solubility | DMSO: ≥20 mg/mL |
storage temp. | 2-8°C |
Features and Benefits: | This compound is featured on the Glutamate Receptors (Ion Channel Family) ![]() ![]() |
General description: | ZK 200775 is a selective AMPA/kainite receptor antagonist with very low affinity for NMDA associated binding sites (Ki for CNQX binding site = 32 nM vs. 2.8 uM for DCKA binding site.) ZK 200775 displays superior PK and safety profiles in in vivo studies compared to quinoxalinedione antagonists such as NBQX, showing no effects on motor behavior or cardiac events at efficacious doses in rat. Additionally, unlike other quinoxalinediones, ZK 200775 is water soluble, making this a desirable tool compound for in vivo studies. |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |