Acetylcholine chloride
USP/1008501 - United States Pharmacopeia (USP) Reference Standard
Synonym: ACh
CAS Number: 60-31-1
Empirical Formula (Hill Notation): C7H16ClNO2
Molecular Weight: 181.66
MDL Number: MFCD00011698
Linear Formula: (CH3)3N+CH2CH2OCOCH3Cl-
Product Type: Chemical
| API family | acetylcholine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C7H16NO2.ClH/c1-7(9)10 |
| InChI key | JUGOREOARAHOCO-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | 146-150 °C (lit.) |
| SMILES string | [Cl-].CC(=O)OCC[N+](C)(C) |
| storage temp. | 2-8°C |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Acetylcholine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Acetylcholine Chloride for Ophthalmic Solution • Methacholine Chloride |
| Biochem/physiol Actions: | Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 146-150 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |