Amifostine thiol
USP/1019428 - United States Pharmacopeia (USP) Reference Standard
Synonym: WR-1065; 2-
CAS Number: 14653-77-1
Empirical Formula (Hill Notation): C5H14N2S · 2HCl
Molecular Weight: 207.16
MDL Number: MFCD00460339
Linear Formula: C5H14N2S · 2HCl
Product Type: Chemical
API family | amifostine |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C5H14N2S.2ClH/c6-2-1-3 |
InChI key | XDRLRDHLCIFZIW-UHFFFAOYSA |
manufacturer/tradename | USP |
SMILES string | Cl.Cl.NCCCNCCS |
storage temp. | −20°C |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Amifostine thiol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
Biochem/physiol Actions: | WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Symbol | GHS05,GHS07 |
Signal word | Danger |
Hazard statements | H302 - H318 |
Precautionary statements | P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 41116107 |