Amitriptyline hydrochloride
USP/1029002 - United States Pharmacopeia (USP) Reference Standard
CAS Number: 549-18-8
Empirical Formula (Hill Notation): C20H23N · HCl
Molecular Weight: 313.86
MDL Number: MFCD00012537
Linear Formula: C20H23N · HCl
Product Type: Chemical
| API family | amitriptyline |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C20H23N.ClH/c1-21(2)15 |
| InChI key | KFYRPLNVJVHZGT-UHFFFAOYSA |
| manufacturer/tradename | USP |
| SMILES string | Cl[H].CN(C)CCC=C1c2cccc |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Amitriptyline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
| Biochem/physiol Actions: | Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 - H319 - H361d - H410 |
| Precautionary statements | P201 - P273 - P301 + P310 + P330 - P305 + P351 + P338 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |