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Azithromycin

USP/1046056 - United States Pharmacopeia (USP) Reference Standard

Synonym: Azithromycin dihydrate; N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A; CP-62993

CAS Number: 117772-70-0
Empirical Formula (Hill Notation): C38H72N2O12 · 2H2O
Molecular Weight: 785.02
MDL Number: MFCD01862248
Linear Formula: C38H72N2O12 · 2H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1046056-200MG 200 mg
 $463.00
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application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C38H72N2O12.2H2O/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28;;/h20-33,35,41-43,45-46H,15-19H2,1-14H3;2*1H2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-;;/m1../s1
InChI key SRMPHJKQVUDLQE-KUJJYQHYSA-N
manufacturer/tradename USP
SMILES string O.O.CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: It was used as calibration standard at concentrations 3.90, 5.85, 7.80, 9.75 and 11.70 mg/mL during HPLC analysis to determine azithromycin in tablets and capsules.
Biochem/physiol Actions: Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.
General description: Azithromycin is a subclass of macrolides consisting of 15-membered macrocyclic lactone ring to which sugar moieties are linked.
Other Notes: Sales restrictions may apply.
Other Notes: USP issued SDS can be found here .
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41116107

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