Betamethasone
USP/1066009 - United States Pharmacopeia (USP) Reference Standard
Synonym: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16β-methylprednisolone
CAS Number: 378-44-9
Empirical Formula (Hill Notation): C22H29FO5
Molecular Weight: 392.46
MDL Number: MFCD00062969
Linear Formula: C22H29FO5
Product Type: Chemical
agency | USP |
API family | betamethasone |
application(s) | pharmaceutical (small molecule) |
biological source | synthetic |
color | white to off-white |
density | 0.305 g/cm3 at 25 °C (77°F) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C22H29FO5/c1-12-8-16-1 |
InChI key | UREBDLICKHMUKA-DVTGEIKXSA |
manufacturer/tradename | USP |
mp | 235-237 °C (lit.) |
447.8-473 °F (231—245°C; decomposes) | |
packaging | pkg of 200 mg |
SMILES string | [H][C@@]12C[C@H](C)[C@](O |
solubility | acetone: sparingly soluble |
chloroform: very slightly soluble | |
ethanol: sparingly soluble | |
ether: very slightly soluble | |
methanol: sparingly soluble | |
water: insoluble | |
storage temp. | 2-8°C |
vapor pressure | <0.0000001 kPa ( 25 °C) |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Betamethasone USP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques. |
General description: | Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs). This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Symbol | GHS08 |
Signal word | Danger |
Hazard statements | H360FD - H373 |
Precautionary statements | P202 - P260 - P280 - P308 + P313 - P405 - P501 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 235-237 °C (lit.); 447.8-473 °F (231—245°C; decomposes) |
Density | 0.305 g/cm3 at 25 °C (77°F) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |