Biochanin A
USP/1071381 - United States Pharmacopeia (USP) Reference Standard
Synonym: 4′-Methylgenistein; 5,7-Dihydroxy-4′-methoxyisoflavone; Genistein 4′-methyl ether; Olmelin
CAS Number: 491-80-5
Empirical Formula (Hill Notation): C16H12O5
Molecular Weight: 284.26
MDL Number: MFCD00006839
Linear Formula: C16H12O5
Product Type: Chemical
| API family | biochanin |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C16H12O5/c1-20-11-4-2- |
| InChI key | WUADCCWRTIWANL-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | 210-213 °C (lit.) |
| SMILES string | COc1ccc(cc1)C2=COc3cc(O)c |
| storage temp. | 2-8°C |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Biochem/physiol Actions: | Biochanin A is an isoflavone phytoestrogen found in red clover (Trifolium pratense) that is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 210-213 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |