Dactinomycin

USP/1162400 - United States Pharmacopeia (USP) Reference Standard

Synonym: Actinomycin D; Actinomycin C₁; Actinomycin IV; Dactinomycin

CAS Number: 50-76-0
Empirical Formula (Hill Notation): C₆₂H₈₆N₁₂O₁₆
Molecular Weight: 1255.42
MDL Number: MFCD00005033
Linear Formula: C₆₂H₈₆N₁₂O₁₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-1162400-50MG	50 mg	$1110.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	dactinomycin
application(s)	pharmaceutical (small molecule)
color	red, powder
format	neat
grade	pharmaceutical primary standard
InChI	1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
InChI key	RJURFGZVJUQBHK-IIXSONLDSA-N
manufacturer/tradename	USP
mp	251-253
SMILES string	CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3OC4=C(C)C(=O)C(N)=C(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)C4=Nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]7CCCN7C1=O

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Dactinomycin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Dactinomycin for Injection
Biochem/physiol Actions:	Actinomycin D inhibits the proliferation of cells by forming a stable complex with double-stranded DNA, inhibiting DNA-primed RNA synthesis and causing single-stranded breaks in DNA. It has been shown to be an inhibitor of the minus-strand transfer step in reverse transcriptase.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H300 - H350 - H360FD
Precautionary statements	P201 - P202 - P264 - P270 - P280 - P301 + P310
RIDADR	UN 2811 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	251-253
UNSPSC	41116107

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