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Darifenacin hydrobromide

USP/1164200 - United States Pharmacopeia (USP) Reference Standard

Synonym: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide hydrobromide; UK 88525-04

CAS Number: 133099-07-7
Empirical Formula (Hill Notation): C28H30N2O2 · HBr
Molecular Weight: 507.46
MDL Number: MFCD08141803
Linear Formula: C28H30N2O2 · HBr
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1164200-150MG 150 mg
 $966.00
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API family darifenacin
application(s) pharmaceutical
form solid
InChI 1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
InChI key UQAVIASOPREUIT-VQIWEWKSSA-N
manufacturer/tradename USP
SMILES string O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Darifenacin hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Biochem/physiol Actions: Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome.
Biochem/physiol Actions: Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41116107

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