Dexamethasone

USP/1176007 - United States Pharmacopeia (USP) Reference Standard

Synonym: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F

CAS Number: 50-02-2
Empirical Formula (Hill Notation): C₂₂H₂₉FO₅
Molecular Weight: 392.46
MDL Number: MFCD00064136
Linear Formula: C₂₂H₂₉FO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-1176007-125MG	125 mg	$412.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	USP
API family	dexamethasone
application(s)	pharmaceutical (small molecule)
biological source	synthetic
color	white
format	neat
grade	pharmaceutical primary standard
InChI	1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key	UREBDLICKHMUKA-CXSFZGCWSA-N
manufacturer/tradename	USP
mp	262-264 °C (lit.)
packaging	pkg of 125 mg
SMILES string	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
solubility	acetone: sparingly soluble
	chloroform: slightly soluble
	ethanol: sparingly soluble
	ether: very slightly soluble
	methanol: sparingly soluble
	water: practically insoluble
storage temp.	2-8°C
vapor pressure	<0.0000001 kPa ( 25 °C)

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Dexamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Ciprofloxacin and Dexamethasone Otic Suspension • Dexamethasone • Dexamethasone Compounded Oral Suspension • Dexamethasone Elixir • Dexamethasone Injection • Dexamethasone Ophthalmic Suspension • Dexamethasone Oral Solution
Biochem/physiol Actions:	Glucocorticoid anti-inflammatory agent
Biochem/physiol Actions:	Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

Symbol	GHS08
Signal word	Danger
Hazard statements	H360FD
Precautionary statements	P201 - P202 - P280 - P308 + P313 - P405 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	262-264 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	41116107

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