Dibutyl phthalate
USP/1187080 - United States Pharmacopeia (USP) Reference Standard
Synonym: n-Butyl phthalate; DBP; Phthalic acid dibutyl ester
CAS Number: 84-74-2
Empirical Formula (Hill Notation): C16H22O4
Molecular Weight: 278.34
MDL Number: MFCD00009441
Linear Formula: C6H4-1,2-[CO2(CH2)3CH3]2
Product Type: Chemical
| API family | dibutyl phthalate |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| autoignition temp. | 756 °F |
| bp | 340 °C (lit.) |
| density | 1.043 g/mL at 25 °C (lit.) |
| expl. lim. | 0.47 %, 236 °F |
| form | liquid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C16H22O4/c1-3-5-11-19- |
| InChI key | DOIRQSBPFJWKBE-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | −35 °C (lit.) |
| refractive index | n |
| SMILES string | CCCCOC(=O)c1ccccc1C(=O)OC |
| vapor density | 9.6 (vs air) |
| vapor pressure | 1 mmHg ( 147 °C) |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Plasticizer |
| General description: | Dibutyl phthalate (DBP) is a plasticizer commonly used in the formulation of biologics to improve the flexibility and stability of polymeric materials. It plays an essential role in the production of drug delivery devices and packaging for biologics. By enhancing the physical properties of polymers, DBP contributes to the reliability and performance of biologic products, particularly those in extended-release or controlled-release systems. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| General description: | This compound is listed in the SVHC (Substances of very high concern) candidate list   of ECHA (European Chemicals Agency) |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
| Other Notes: | This product is part of USP Biologics Program. |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha |
| Symbol |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H360FD - H410 |
| Precautionary statements | P201 - P273 - P308 + P313 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 367.7 °F - open cup |
| Flash Point(C) | 186.5 °C - open cup |
| bp | 340 °C (lit.) |
| mp | −35 °C (lit.) |
| Density | 1.043 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 41116107 |