Dihydrostreptomycin sulfate
USP/1203008 - United States Pharmacopeia (USP) Reference Standard
Synonym: Dihydrostreptomycin sesquisulfate
CAS Number: 5490-27-7
Empirical Formula (Hill Notation): C21H41N7O12·1.5H2SO4
Molecular Weight: 730.71
MDL Number: MFCD00070252
Linear Formula: C21H41N7O12 · 3/2H2SO4
Product Type: Chemical
| API family | dihydrostreptomycin |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| form | solid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/2C21H41N7O12.3H2O4S/c2 |
| InChI key | CZWJCQXZZJHHRH-YZTFXSNBSA |
| manufacturer/tradename | USP |
| mol wt | monograph mol wt. 1461.44 |
| SMILES string | OS(O)(=O)=O.OS(O)(=O)=O.O |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Dihydrostreptomycin sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Dihydrostreptomycin Injection • Dihydrostreptomycin Sulfate • Dihydrostreptomycin Sulfate Boluses • Penicillin G Procaine and Dihydrostreptomycin Sulfate Injectable Suspension • Penicillin G Procaine and Dihydrostreptomycin Sulfate Intramammary Infusion • Penicillin G Procaine, Dihydrostreptomycin Sulfate, Chlorpheniramine Maleate, and Dexamethasone Injectable Suspension |
| General description: | Dihydrostreptomycin sulfate is a semi-synthetic aminoglycoside antibiotic derived from streptomycin. It binds to bacterial ribosomes, disrupting protein synthesis. The USP standard supports microbiological testing and chromatographic identity confirmation. The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| Other Notes: | ((C21H41N7O12)2 · 3H2SO4) |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of the USP Biologics program. |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302 - H361fd |
| Precautionary statements | P280 - P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |


