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Doxycycline hyclate

USP/1226003 - United States Pharmacopeia (USP) Reference Standard

Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate

CAS Number: 24390-14-5
Empirical Formula (Hill Notation): C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
Molecular Weight: 512.94
MDL Number: MFCD07357237
Linear Formula: C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-1226003-200MG 200 mg
$436.00
1/EA
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API family doxycycline
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1
InChI key HALQELOKLVRWRI-ZVACAFRPSA-N
manufacturer/tradename USP
SMILES string Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58
storage temp. 2-8°C
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Doxycycline hyclate USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard, system suitability stock, and sensitivity solution for the assay, impurity analysis, and performance test by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
• Doxycycline Hyclate
• Doxycycline Hyclate Delayed-Release Tablet  
• Doxycycline Tablets  
• Doxycycline Capsules  
• Doxycycline Hyclate Tablets
Biochem/physiol Actions: Mode of Action: Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi.

Activity Spectrum: Effective against a broad spectrum inhibitor of matrix metalloproteinases in vivo.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 41116107

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