Dutasteride

USP/1229922 - United States Pharmacopeia (USP) Reference Standard

Synonym: (5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide

CAS Number: 164656-23-9
Empirical Formula (Hill Notation): C₂₇H₃₀F₆N₂O₂
Molecular Weight: 528.53
MDL Number: MFCD00937869
Linear Formula: C₂₇H₃₀F₆N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-1229922-200MG	200 mg	$607.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	dutasteride
application(s)	pharmaceutical (small molecule)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1
InChI key	JWJOTENAMICLJG-QWBYCMEYSA-N
manufacturer/tradename	USP
SMILES string	O=C1C=C[C@@]2(C)[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(NC5=CC(C(F)(F)F)=CC=C5C(F)(F)F)=O)([H])N1
storage temp.	2-8°C

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Therapeutic Applications for Benign Prostatic Hyperplasia: Dutasteride, a potent 5-alpha-reductase inhibitor, is pivotal in developing plant-derived bioactive metabolites as alternatives for treating benign prostatic hyperplasia (BPH). This research highlights the potential of dutasteride in enhancing the efficacy and safety of prostate health treatments (Krishnamoorthi et al., 2024 ). Innovative Formulations for Hair Loss Treatment: Dutasteride is explored for its compatibility and efficacy in TrichoFoam, a natural vehicle for hair foams. This study demonstrates the potential of dutasteride in combination with other agents for treating androgenetic alopecia, providing a synergistic approach to hair loss management (Polonini et al., 2024 ). Impact on Sexual Dysfunction: The implications of dutasteride therapy for androgenetic alopecia on sexual dysfunction are critically analyzed. This global propensity-score-matched retrospective cohort study enhances our understanding of the side effects associated with long-term use of 5-alpha-reductase inhibitors (Lauck et al., 2024 ). Hormonal Background of Hair Loss: Dutasteride′s role is examined in the context of non-scarring alopecias, where hormonal imbalances play a significant part. This review discusses the hormonal mechanisms influenced by dutasteride, shedding light on its comprehensive effects in hair loss treatments (Owecka et al., 2024 ). Prostate Cancer Screening and Management: The effect of 5-alpha reductase inhibitors like dutasteride on the accuracy of prostate cancer detection through MRI is scrutinized. This research underscores the importance of understanding the pharmacological actions of dutasteride in improving diagnostic and management strategies for prostate cancer (Morote et al., 2024 ).
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	41116107

To Order From a Quote