Erythromycin B
USP/1242010 - United States Pharmacopeia (USP) Reference Standard
Synonym: 12-Deoxyerythromycin
CAS Number: 527-75-3
Empirical Formula (Hill Notation): C37H67NO12
Molecular Weight: 717.93
MDL Number: MFCD01729130
Linear Formula: C37H67NO12
Product Type: Chemical
| API family | erythromycin |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C37H67NO12/c1-14-26-20 |
| InChI key | IDRYSCOQVVUBIJ-ZTOAHLHUSA |
| manufacturer/tradename | USP |
| SMILES string | N(C1C(C(OC(C1)C)O[C@H]2[C |
| storage temp. | −20°C |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. |
| Biochem/physiol Actions: | Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site. Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria. |
| Disclaimer: | This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Legal Information: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
| Preparation Note: | This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 41116107 |