Ethyl acetate
USP/1265402 - United States Pharmacopeia (USP) Reference Standard
Synonym: EtOAc
CAS Number: 141-78-6
Empirical Formula (Hill Notation): C4H8O2
Molecular Weight: 88.11
MDL Number: MFCD00009171
Linear Formula: CH3COOC2H5
Product Type: Chemical
| application(s) | USP Biologics pharmaceutical (small molecule) |
| autoignition temp. | 801 °F |
| bp | 76.5-77.5 °C (lit.) |
| density | 0.902 g/mL at 25 °C (lit.) |
| expl. lim. | 2.2-11.5 %, 38 °F |
| form | liquid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C4H8O2/c1-3-6-4(2)5/h3 |
| InChI key | XEKOWRVHYACXOJ-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | −84 °C (lit.) |
| refractive index | n |
| SMILES string | CCOC(C)=O |
| vapor density | 3 (20 °C, vs air) |
| vapor pressure | 73 mmHg ( 20 °C) |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Ethyl acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
| General description: | Ethyl acetate, a volatile ester, is frequently employed in microbiology as a solvent and extraction agent. In the pharmaceutical and biologics industries, it is particularly useful in processes where a non-polar solvent is needed to extract bioactive compounds or for purification steps. Ethyl acetate is valued for its relatively low toxicity and efficient solvent properties, contributing to the formulation of biologic products while maintaining quality and compliance with regulatory standards. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of USP Biologics Program. |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H336 |
| Precautionary statements | P210 - P305 + P351 + P338 - P370 + P378 - P403 + P235 |
| RIDADR | UN1173 - class 3 - PG 2 - Ethyl acetate |
| WGK Germany | WGK 1 |
| Flash Point(F) | 26.6 °F - closed cup |
| Flash Point(C) | -3.0 °C - closed cup |
| Supplemental Hazard Statements | EUH066 |
| bp | 76.5-77.5 °C (lit.) |
| mp | −84 °C (lit.) |
| Density | 0.902 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 41116107 |