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Famciclovir

USP/1269152 - United States Pharmacopeia (USP) Reference Standard

Synonym: 2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ester; BRL 42810

CAS Number: 104227-87-4
Empirical Formula (Hill Notation): C14H19N5O4
Molecular Weight: 321.33
MDL Number: MFCD00866964
Linear Formula: C14H19N5O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-1269152-200MG 200 mg
$436.00
1/EA
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API family famciclovir
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChI key GGXKWVWZWMLJEH-UHFFFAOYSA-N
manufacturer/tradename USP
SMILES string CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
storage temp. 2-8°C
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Famciclovir USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
•  Famciclovir Tablets
•  Famciclovir Compounded Oral Suspension
Biochem/physiol Actions: Famciclovir is an antiretroviral guanosine analog used to treat herpesvirus infections and hepatitis B. Famciclovir is rapidly converted to penciclovir. Viral thymidine kinase phosphorylates penciclovir to a monophosphate form that celular kinases convert in turn to penciclovir triphosphate. Penciclovir triphosphate competitively inhibits viral DNA polymerase and thus viral replication. Prolonged administration can lead to resistance; it is often manifested as selection of pre-existing resistant strains with mutations in the reverse transcriptase domain of the DNA polymerase gene.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 41116107

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