Famotidine
USP/1269200 - United States Pharmacopeia (USP) Reference Standard
Synonym: Famotidine; N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine
CAS Number: 76824-35-6
Empirical Formula (Hill Notation): C8H15N7O2S3
Molecular Weight: 337.45
MDL Number: MFCD00079297
Linear Formula: C8H15N7O2S3
Product Type: Chemical
agency | USP |
API family | famotidine |
application(s) | pharmaceutical (small molecule) |
biological source | synthetic |
color | white to pale yellow-white |
form | powder |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C8H15N7O2S3/c9-6(15-20 |
InChI key | XUFQPHANEAPEMJ-UHFFFAOYSA |
manufacturer/tradename | USP |
mp | 325.4-327.2 °F (163—164°C) |
packaging | pkg of 125 mg |
SMILES string | NC(N)=Nc1nc(CSCCC(=N)NS |
solubility | acetone: practically insoluble |
chloroform: practically insoluble | |
DMF: freely soluble | |
ethanol: practically insoluble | |
ether: practically insoluble | |
ethyl acetate: practically insoluble | |
glacial acetic acid: freely soluble | |
methanol: slightly soluble | |
water: very slightly soluble | |
storage condition | protect from light |
storage temp. | 2-8°C |
vapor pressure | <0.0000001 kPa ( 25 °C) |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Famotidine can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by various analytical techniques.(10) |
Biochem/physiol Actions: | H2 histamine receptor antagonist; anti-ulcer agent |
General description: | Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans. This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 325.4-327.2 °F (163—164°C) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |