Flucytosine
USP/1272000 - United States Pharmacopeia (USP) Reference Standard
Synonym: 5-Fluorocytosine; 4-
CAS Number: 2022-85-7
Empirical Formula (Hill Notation): C4H4FN3O
Molecular Weight: 129.09
MDL Number: MFCD00006035
Linear Formula: C4H4FN3O
Product Type: Chemical
API family | flucytosine |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C4H4FN3O/c5-2-1-7-4(9) |
InChI key | XRECTZIEBJDKEO-UHFFFAOYSA |
manufacturer/tradename | USP |
mp | 298-300 °C (dec.) (lit.) |
SMILES string | NC1=NC(=O)NC=C1F |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Flucytosine USP reference standard for use in specified quality tests and assays. Also used to prepare standard and sensitivity solutions for the assay, identification, performance test, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP): • Flucytosine • Flucytosine Capsules • Flucytosine Compounded Oral Suspension |
Biochem/physiol Actions: | Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() ![]() |
Other Notes: | Sales restrictions may apply. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H361 |
Precautionary statements | P280 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 298-300 °C (dec.) (lit.) |
UNSPSC | 41116107 |