Synonym: Fluocinonide; (6α,11β,16α)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; Lonide
CAS Number: 356-12-7
Empirical Formula (Hill Notation): C26H32F2O7
Molecular Weight: 494.52
MDL Number: MFCD00079302
Linear Formula: C26H32F2O7
Product Type: Chemical
API family |
fluocinonide |
application(s) |
pharmaceutical (small molecule) |
format |
neat |
grade |
pharmaceutical primary standard |
InChI |
1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1 |
InChI key |
WJOHZNCJWYWUJD-IUGZLZTKSA-N |
manufacturer/tradename |
USP |
SMILES string |
CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C |
Analysis Note: |
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: |
Fluocinonide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
Biochem/physiol Actions: |
Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocorticolids were identified as smoothend agonists. Flucinonide induces expression of Gli-reporter luciferase in Shh-LIGHT2 cells. |
General description: |
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia ![External link](https://krackeler.com/images/sigma/ext-link.gif) . |
Other Notes: |
Sales restrictions may apply. |