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Fluocinonide

USP/1276001 - United States Pharmacopeia (USP) Reference Standard

Synonym: Fluocinonide; (6α,11β,16α)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione; Lonide

CAS Number: 356-12-7
Empirical Formula (Hill Notation): C26H32F2O7
Molecular Weight: 494.52
MDL Number: MFCD00079302
Linear Formula: C26H32F2O7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1276001-200MG 200 mg
 $455.00
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API family fluocinonide
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1
InChI key WJOHZNCJWYWUJD-IUGZLZTKSA-N
manufacturer/tradename USP
SMILES string CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Fluocinonide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
•  Fluocinonide Ointment
•  Fluocinonide Cream
•  Fluocinonide Gel
•  Fluocinonide Topical Solution
Biochem/physiol Actions: Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocorticolids were identified as smoothend agonists. Flucinonide induces expression of Gli-reporter luciferase in Shh-LIGHT2 cells.
Biochem/physiol Actions: very potent corticosteroid
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
UNSPSC 41116107

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