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Fluticasone propionate

USP/1285873 - United States Pharmacopeia (USP) Reference Standard

Synonym: (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester

CAS Number: 80474-14-2
Empirical Formula (Hill Notation): C25H31F3O5S
Molecular Weight: 500.57
MDL Number: MFCD00866007
Linear Formula: C25H31F3O5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1285873-100MG 100 mg
 $2070.00
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API family fluticasone
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
InChI key WMWTYOKRWGGJOA-CENSZEJFSA-N
manufacturer/tradename USP
SMILES string CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Fluticasone propionate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
•  Fluticasone Propionate and Salmeterol Inhalation Aerosol®
•  Fluticasone Propionate and Salmeterol Inhalation Powder
•  Fluticasone Propionate Cream
•  Fluticasone Propionate Inhalation Aerosol®
•  Fluticasone Propionate Inhalation Powder
•  Fluticasone Propionate Lotion
Biochem/physiol Actions: Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Legal Information: Aerosol is a registered trademark of Cytec Technology Corp.
Other Notes: Sales restrictions may apply.
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41116107

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