Goserelin acetate

USP/1297205 - United States Pharmacopeia (USP) Reference Standard

Synonym: [D-Ser(tBu)⁶,Azagly¹⁰]-LHRH acetate salt

CAS Number: 145781-92-6
Empirical Formula (Hill Notation): C₅₉H₈₄N₁₈O₁₄
Molecular Weight: 1269.41
MDL Number: MFCD01747329
Linear Formula: C₅₉H₈₄N₁₈O₁₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-1297205-100MG	100 mg	$1430.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	goserelin
application(s)	USP Biologics pharmaceutical (small molecule)
form	powder
format	neat
grade	pharmaceutical primary standard
InChI	1S/C59H84N18O14.C2H4O2/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38;1-2(3)4/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90);1H3,(H,3,4)/t38-,39-,40-,41-,42-,43-,44-,45+,46-;/m0./s1
InChI key	IKDXDQDKCZPQSZ-JHYYTBFNSA-N
manufacturer/tradename	USP
SMILES string	CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NNC(N)=O
storage temp.	−20°C

Amino Acid Sequence:	Glp-His-Trp-Ser-Tyr-Ser(tBu)-Leu-Arg-Pro-azaGly-NH2
Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Goserelin acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Goserelin Implants
Biochem/physiol Actions:	Goserelin is a synthetic analog of LHRH (leutinizing hormone releasing hormone). Goserelin is a LHRH agonist It is used in prostate cancer and breast cancer therapies and also in the treatment of endometriosis.
General description:	A GnRH analog utilized in hormone-sensitive cancers. Peptide family: Goserelin The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Other Notes:	Sales restrictions may apply.
Other Notes:	This product is part of the USP Biologics program.
Other Notes:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .

Symbol	GHS08
Signal word	Danger
Hazard statements	H360
Precautionary statements	P201 - P280 - P308 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	41116107

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