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Hydroxychloroquine sulfate

USP/1327000 - United States Pharmacopeia (USP) Reference Standard

Synonym: Hydroxychloroquine sulfate; 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate

CAS Number: 747-36-4
Empirical Formula (Hill Notation): C18H26ClN3O · H2SO4
Molecular Weight: 433.95
EC Number: 212-019-3
MDL Number: MFCD00078203
Linear Formula: C18H26ClN3O · H2SO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1327000-200MG 200 mg
 $455.00
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agency USP
API family hydroxychloroquine
application(s) pharmaceutical (small molecule)
biological source synthetic
color white to off-white
format neat
grade pharmaceutical primary standard
InChI 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChI key JCBIVZZPXRZKTI-UHFFFAOYSA-N
manufacturer/tradename USP
mp 388.4 °F (198°C; 240°C)
packaging pkg of 200 mg
pH 3.5-5.5 (1% in aqueous solution, pH <6.0)
SMILES string OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
solubility chloroform: practically insoluble
  ethanol: practically insoluble
  ether: practically insoluble
  water: soluble
storage condition protect from light
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Hydroxychloroquine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
•  Hydroxychloroquine Sulfate Tablets
•  Hydroxychloroquine Sulfate Compounded Oral Suspension
•  Chloroquine Phosphate
Biochem/physiol Actions: Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor.
Biochem/physiol Actions: Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .

Hydroxychloroquine Sulfate is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
Other Notes: Sales restrictions may apply.
mp 388.4 °F (198°C; 240°C)
UNSPSC 41116107

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