Iloperidone
USP/1336249 - United States Pharmacopeia (USP) Reference Standard
Synonym: Iloperidone; 1-
CAS Number: 133454-47-4
Empirical Formula (Hill Notation): C24H27FN2O4
Molecular Weight: 426.48
MDL Number: MFCD00866688
Linear Formula: C24H27FN2O4
Product Type: Chemical
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C24H27FN2O4/c1-16(28)1 |
InChI key | XMXHEBAFVSFQEX-UHFFFAOYSA |
manufacturer/tradename | USP |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Biochem/physiol Actions: | Iloperidone is an atypical antipsychotic, a combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Iloperidone targets a selective set of dopamine, serotonin and also norepinephrine receptor subtypes. Like similar atypical antipsychotics, Iloperidone has higher affinity for the 5-HT2A receptor (Ki < 10 nM) than for the D2 receptor (Ki = 10–100) nM). Iloperidone has high affinity for dopamine D3 (Ki < 10 nM) and lower affinity for other serotonin or dopamine subtypes. Unlike most atypical antipsychotics, Iloperidone also has high affinity for norepinephrine alpha1 receptors (Ki < 10 nM) which may contribute to the drug’s efficacy on mood and cognition. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() ![]() |
Other Notes: | Sales restrictions may apply. |
Other Notes: | USP issued SDS can be found here ![]() ![]() |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 - H413 |
Precautionary statements | P301 + P330 + P331 + P310 |
RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 41116107 |