Insulin human
USP/1342106 - United States Pharmacopeia (USP) Reference Standard
CAS Number: 11061-68-0
Empirical Formula (Hill Notation): C257H383N65O77S6
Molecular Weight: 5807.57
MDL Number: MFCD00131380
Linear Formula: C257H383N65O77S6
Product Type: Chemical
API family | insulin |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI key | PBGKTOXHQIOBKM-FHFVDXKLSA |
manufacturer/tradename | USP |
storage temp. | −20°C |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Insulin human USP reference standard suitable for use in specified USP compendial tests and assays. Also, for use with USP monographs such as: • Insulin Human Injection • Human Insulin Isophane Suspension and Human Insulin Injection • Isophane Insulin Human Suspension |
Biochem/physiol Actions: | Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . Insulin Human is a peptide hormone made up of two chains consisting of 51 amino acids, which closely resembles the natural insulin produced by the pancreas' beta cells. The A-chain comprises 21 amino acids, while the B-chain is made up of 30 amino acids. It is obtained either by modifying insulin from the porcine pancreas using enzymes to adjust the amino acid sequence, or by using recombinant DNA technology to produce it. |
Other Notes: | InChI: 1S/C257H383N65O77S6/c1-29 |
Other Notes: | Sales restrictions may apply. |
Other Notes: | This product is part of the USP Biologics program. |
RIDADR | NONH for all modes of transport |
WGK Germany | nwg |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 41116107 |