Insulin (Pork)
USP/1342300 - United States Pharmacopeia (USP) Reference Standard
Synonym: Insulin from porcine pancreas; Insulin from hog pancreas
CAS Number: 12584-58-6
Empirical Formula (Hill Notation): C256H381N65O76S6
Molecular Weight: 5777.54
MDL Number: MFCD00131380
Linear Formula: C256H381N65O76S6
Product Type: Chemical
| application(s) | USP Biologics pharmaceutical (small molecule) |
| form | powder |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI key | NOESYZHRGYRDHS-ZYCCASTOSA |
| manufacturer/tradename | USP |
| storage temp. | −20°C |
| Application: | Insulin (Pork) USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Insulin • Insulin Injection • Isophane Insulin Suspension • Extended Insulin Zinc Suspension • Prompt Insulin Zinc Suspension • Insulin Zinc Suspension |
| Biochem/physiol Actions: | Regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. |
| Biochem/physiol Actions: | Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. |
| General description: | Insulin (Pork) is a biologically derived insulin obtained from porcine pancreas. It shares a high degree of homology with human insulin, differing by a single amino acid. This insulin variant has been historically used in diabetes management. The USP biologics proteins category provides critical standards and reference materials necessary for the development and manufacturing of therapeutic proteins. These proteins, which can be naturally derived or genetically engineered, are essential in treating various diseases and conditions, ensuring that they meet quality, safety, and efficacy standards. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| Other Notes: | InChI: 1S/C256H381N65O76S6/c1-29 |
| Other Notes: | All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of the USP Biologics program. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 41116107 |