Lopinavir

USP/1370101 - United States Pharmacopeia (USP) Reference Standard

CAS Number: 192725-17-0
Empirical Formula (Hill Notation): C₃₇H₄₈N₄O₅
Molecular Weight: 628.80
Linear Formula: C₃₇H₄₈N₄O₅
Product Type: Chemical

agency	USP/NF
API family	lopinavir
application(s)	pharmaceutical (small molecule)
biological source	synthetic
color	white to off-white
form	powder
format	neat
grade	pharmaceutical primary standard
InChI	1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
InChI key	KJHKTHWMRKYKJE-SUGCFTRWSA-N
manufacturer/tradename	USP
mp	255.2-260.6 °F (124—127°C)
packaging	pkg of 350 mg
solubility	chloroform: soluble
	isopropanol: soluble
	methanol: freely soluble
	methylene chloride: freely soluble
	water: practically insoluble
storage condition	protect from light
storage temp.	2-8°C

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Lopinavir may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by chromatography techniques.
General description:	Lopinavir is an antiretroviral agent and a protease inhibitor indicated for the management of human immunodeficiency virus (HIV) infection. It is a key component of Kaletra, the co-formulation of lopinavir and ritonavir.
Other Notes:	Sales restrictions may apply.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable