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Loratadine Related Compound A

USP/1370280 - United States Pharmacopeia (USP) Reference Standard

Synonym: Desloratadine; 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine; Clarinex®; NSC 675447

CAS Number: 100643-71-8
Empirical Formula (Hill Notation): C19H19ClN2
Molecular Weight: 310.82
MDL Number: MFCD00871949
Linear Formula: C19H19ClN2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1370280-15MG 15 mg
 $1380.00
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API family loratadine
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI key JAUOIFJMECXRGI-UHFFFAOYSA-N
manufacturer/tradename USP
SMILES string Clc1ccc2c(CCc3cccnc3C2=C4CCNCC4)c1
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Loratadine Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
• Loratadine Orally Disintegrating Tablets
• Loratadine Chewable Tablets
• Loratadine Capsules
Biochem/physiol Actions: Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Legal Information: Clarinex is a registered trademark of Schering Corp.
Other Notes: Sales restrictions may apply.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41116107

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