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Methylene blue

USP/1428008 - United States Pharmacopeia (USP) Reference Standard

Synonym: 3,7-bis(Dimethylamino)phenazathionium chloride; Tetramethylthionine chloride

CAS Number: 122965-43-9
Empirical Formula (Hill Notation): C16H18ClN3S · xH2O
Molecular Weight: 319.85 (anhydrous basis)
EC Number: 200-515-2
MDL Number: MFCD00150006
Linear Formula: C16H18ClN3S · xH2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-1428008-750MG 750 mg
$436.00
1/EA
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application(s) pharmaceutical (small molecule)
InChI 1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
InChI key WQVSELLRAGBDLX-UHFFFAOYSA-M
manufacturer/tradename USP
SMILES string CN(C)C1=CC=C2C(SC(C3=N2)=CC(C=C3)=[N+](C)C)=C1.[H]O[H].[Cl-]
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application:


  • Methylene blue as a redox indicator: Recent research has highlighted the application of methylene blue as a redox indicator in radiation-assisted assembly of nanomolybdenum-functionalized covalent organic frameworks, offering advancements in the synthesis and application of these materials for enhanced catalytic performance (Zhang et al., 2024 ).


  • Methylene blue for photocatalytic reduction: A novel approach in the synthesis of nickel oxide has been utilized to explore methylene blue′s role in photocatalytic reduction, demonstrating its potential in environmental applications to degrade pollutants efficiently (Baytar, 2024 ).


  • Methylene blue in antimicrobial activities: This dye′s application extends to bioactive contexts, where it has been used to enhance the antimicrobial properties of enzymes immobilized on green synthesized magnetic nanoparticles, providing a multifunctional approach to bioengineering (Fahim et al., 2024 ).


  • Methylene blue in enzymatic dye decolorization: The compound also plays a role in the decolorization of dyes, leveraging its properties in bioremediation studies focused on the bioactive and enzymatic potential of marine fungi, highlighting its utility in marine environmental management (Wong Chin et al., 2024 ).


General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Other Notes: USP issued SDS can be found here .
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Colour Index Number 52015
UNSPSC 41116107

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