Oxytetracycline
USP/1491004 - United States Pharmacopeia (USP) Reference Standard
Synonym: Oxytetracycline dihydrate
CAS Number: 6153-64-6
Empirical Formula (Hill Notation): C22H24N2O9 · 2H2O
Molecular Weight: 496.46
EC Number: 201-212-8
MDL Number: MFCD00151234
Linear Formula: C22H24N2O9 · 2H2O
Product Type: Chemical
| API family | oxytetracycline |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| form | solid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C22H24N2O9.H2O/c1-21(3 |
| InChI key | IBZHEBHGZFICKS-IFLJXUKPSA |
| manufacturer/tradename | USP |
| SMILES string | O.[H][C@@]12[C@@H](O)[C@@ |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Oxytetracycline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Oxytetracycline Hydrochloride • Oxytetracycline Injection • Oxytetracycline Tablets • Oxytetracycline for Injection • Oxytetracycline Hydrochloride Capsules • Oxytetracycline Hydrochloride Soluble Powder |
| Biochem/physiol Actions: | Antibiotic produced by Streptomyces rimosus. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation. |
| General description: | Oxytetracycline is a broad-spectrum tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It is effective against a range of Gram-positive and Gram-negative organisms. The USP reference standard ensures assay precision and identity confirmation in oxytetracycline drug products. The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of USP Biologics Program. |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Symbol |   GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H361d - H411 |
| Precautionary statements | P201 - P202 - P273 - P280 - P308 + P313 - P391 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |